It’s critical to know that severe side effects can take place with COMBIVIR, this kind of as a decrease in red and white blood cells and muscle injury. A buildup of lactic acid and an enlarged liver, which includes fatal cases, have been documented hardly ever with some HIV medicines, which include nucleoside analogues.
For HIV-infected persons, periodic blood tests are proposed. If selected adjustments happen in your laboratory outcomes while you are taking COMBIVIR, especially if you develop into anemic or if your white blood cell count falls way too minimal, your treatment may well need to be adjusted your medical professional may possibly prescribe EPIVIR in addition RETROVIR separately in place of COMBIVIR.
Some individuals contaminated with each hepatitis B virus (HBV) and HIV have worsening of hepatitis soon after stopping lamivudine (a component of COMBIVIR). Focus on any modify in therapy with your medical doctor. If you have the two HBV and HIV and cease remedy with COMBIVIR, you ought to be closely monitored by your physician for at the very least several months.
Worsening of liver disease (at times resulting in loss of life) has occurred in sufferers contaminated with both HIV and hepatitis C virus who are using anti-HIV medicines and are also becoming taken care of for hepatitis Do with interferon with or with out ribavirin. If you are taking COMBIVIR as effectively as interferon with or devoid of ribavirin and you expertise aspect results, be sure to inform your doctor.
When you start out using HIV medicines, your immune system could get stronger and could start to combat infections that have been hidden in your entire body, these kinds of as pneumonia, herpes virus or tuberculosis. If you have new signs or symptoms soon after starting your HIV medicines, be positive to talk with your health practitioner.
Improvements in body body fat may possibly occur in some clients taking antiretroviral treatment. These modifications may well involve an improved total of fat in the upper back and neck (“buffalo hump”
, breast, and close to the trunk. Reduction of extra fat from the legs, arms and experience may well also happen. The result in and prolonged-term wellness results of these problems are not regarded at this time.
In medical reports of lamivudine plus zidovudine, aspect results occurring in five% or far more of patients incorporated: headache, upset belly, weakness and fatigue, and nasal indicators.
Inform your health practitioner promptly about any aspect results or other abnormal symptoms you might practical experience. Even though it may well make you healthier, COMBIVIR does not heal HIV.
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